Web欧盟知识产权局 . 西班牙. 芬兰 WebThe human genome encodes thousands of natural antisense long noncoding RNAs (lncRNAs); they play the essential role in regulation of gene expression at multiple levels, including replication, transcription and translation. Dysregulation of antisense lncRNAs plays indispensable roles in numerous biological progress, such as tumour progression, …
LncRNA SOCS2-AS1 promotes the progression of glioma via …
WebBackground: Bladder cancer (BC) is the most commonly occurring malignant tumor of the urinary system worldwide. Long non-coding RNAs (lncRNAs), including lncRNA RNF144A-AS1 (RNF144A-AS1), perform an oncogenic role in BC progression. However, how RNF144A-AS1 is regulated in BC has not been fully investigated, and its role in BC is mostly obscure. WebReduced RNF144A expression was associated with more severe influenza in humans and its expression in patients was a biomarker distinguishing moderate from severe disease. These studies reveal a vital physiological role for RNF144A in maintaining the fidelity of IL-2R signaling in CTLs to prevent severe inflammation in response to infection. the jungle meat packing industry quotes
NEW MARKER OF BREAST TUMORS FROM THE LUMINAL-B …
WebBackground: RNF144A is a membrane-associated E3 ubiquitin ligase.Results: The GXXXG motif within the TM domain of RNF144A mediates its self-association and activation of … Webof amino acids with RNF144A. RNF144A is able to interact with E2-conjugating enzymes UbcH7 and UbcH8 through its RING1 domain, and mutations on IBR or RING2 reduce this … WebSep 1, 2024 · Additionally, RNF144A-AS1 was also induced by TGF-β1. Loss and gain of function assays revealed that RNF144A-AS1 promoted tumor metastasis, angiogenesis, and proliferation. Mechanism exploration indicated RNF144A-AS1 served as a microRNA decoy of miR-30c-2-3p to release LOX. the jungle niles il